|
How the nervous system controls the digestive process
The digestive tract is controlled by neurons of the enteric nervous system. Loss of the ENS is lethal, and yet the way in which it controls digestion is poorly understood.  View project details
|
|
|
Identification and initial characterization of novel transcripts regulated during motor learning.
Co-supervisor: Dr Tim Aumann
The CNS is unique in its spatiotemporal complexity and we still have little understanding of the molecular mechanisms orchestrating development, plasticity or response to disease or injury. Sequencing of the human genome resulted in identification of a relatively small number of predicted protein coding genes, suggesting that this complexity could be derived from expression of splice variants. View project details
|
|
|
Identification of novel inhibitors of Alzheimer’s disease BACE1
Alzheimer’s disease Aß amyloid peptide is produced from its precursor APP, by the action of beta-secretase and gamma-secretase. View project details
|
|
|
Identifying novel metal-mediated cell signal pathways using protein microarrays
Abnormal biometal metabolism is a central feature of many neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases. View project details
|
|
|
Imaging neuronal receptor changes during acquired epileptogenesis using PET and in rat models of temporal lobe epilepsy
| A/Prof. Terence J. O'Brien |
Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy in adults and is often resistant to medical therapy. View project details
|
|
