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The effect of stimulation rate on T- and C- Levels

Dr. David Sly
University of Melbourne

Supervisor:Dr Julia Sarant

When programming a cochlear implant it is necessary to determine the minimum level of stimulation required to evoke an auditory response (i.e. a T-Level) and the highest level of stimulation deemed comfortable by the user (i.e. a C-Level) for each electrode.

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The effect of stress and corticosteroids in the pathogenesis of mesial temporal lobe epilepsy utilising a rat kindling model

A/Prof. Terence J. O'Brien
University of Melbourne

To investigate whether exposure to low-dose corticosteroids and/or stress in early life results in an enhanced predisposition to acquired epileptogenesis in the rat electrical amygdala kindling model of mesial temporal lobe epilepsy.

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The effects of DHA supplementation on the preterm brain using magnetic resonance imaging.

Dr Deanne Thompson
Murdoch Childrens Research Institute

Co-supervisors: Prof Lex W Doyle, Dr Peter J Anderson, and Dr Carly Molloy.

There is evidence that supplementation of Docosahexaenoic Acid (DHA), an omega-3 fatty acid, to lactating mothers improves visual and neurodevelopmental functioning of preterm infants, but the mechanisms by which brain development is improved remain unknown. Neuroimaging will be used to investigate brain structure and connectivity of 6 year-old children born preterm who did or did not receive DHA supplementation from their mother's breastmilk.

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The effects of prematurity on the visual system of children born preterm.

Dr Deanne Thompson
Murdoch Childrens Research Institute

Co-supervisors: Dr Rod Hunt, Dr Peter J Anderson.

One of the many potential difficulties very preterm infants born <30 weeks gestational age or <1250g birth weight face is disruption to visual development. The integrity of the visual pathways is able to be assessed using diffusion MRI. Specifically, tractography is a technique that can provide a 3D virtual representation of the visual tracts, and diffusion measures are able to estimate the axonal integrity and degree of myelination within the white matter tract.

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The effects of toluene exposure on the adolescent brain

Prof. Andrew Lawrence
Florey Neuroscience Institutes

Co-supervisor: Dr Jhodie Duncan

A major focus of our research has been the development of relevant rodent models of addiction. The use of different rodent strains, along with pertinent paradigms has enabled us to address key questions pertinent to addiction, such as the identification of factors implicated in behavioural responses to drugs of abuse and also the chemistry of relapse.

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