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Repairing the auditory system with cochlear implantation and drug delivery
Supervisor: Dr Andrew Wise
Acommon cause of deafness is the loss of sensory hair cells in the innerear that normally convert sound into nerve impulses. The cochlearimplant works by electrically exciting auditory nerves directly tobypass the sensory hair cells that are either damaged or absent.
 View project details
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Role of BDNF in depression and schizophrenia
| Dr. Maarten van den Buuse |
| Mental Health Research Institute |
Supervisor(s):A/Prof Maarten van den Buuse and Dr Rachel Hill
We use behavioural animal models to study neuropsychopharmacological mechanisms involved in depression, schizophrenia and related psychiatric illnesses. In rats or mice, behavioural tests are combined with central and systemic surgical interventions or specific neuropharmacological approaches. State-of-the-art automated equipment is used for detailed behavioural analysis, including photocell activity meters, video-analysis, prepulse inhibition of startle and models of learning and memory. This in vivo work is complemented with receptor autoradiography, and molecular studies on gene expression. View project details
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Role of dietary omega-3 polyunsaturated fatty acids (PUFA) on zinc homeostasisin brain
Alzheimer's Disease is a major neurodegenerative disease affecting many elderly
people. View project details
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Role of IRAP in insulin-responsive tissues
| Florey Neuroscience Institutes |
We were the first group to identify the AT4 receptor as IRAP, the specific binding site for AT4 ligands. View project details
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Role of IRAP in the central nervous system
| Florey Neuroscience Institutes |
Our group proposes that IRAP is a novel target that can be used for the development of therapeutic agents for the treatment of memory disorders. View project details
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